alaabta

Waa maxay Nitric Oxide?

Nitric oxide waa gaas ay soo saaraan unugyo ku lug leh bararka la xiriira xasaasiyadda ama neefta eosinophilic.

Waa maxay FeNO?

Tijaabada Nitric Oxide (FeNO) ee jajaban ee la sii daayo waa hab lagu cabbiro qaddarka nitric oxide ee neefta la sii daayo.Baadhitaankani wuxuu kaa caawin karaa ogaanshaha neefta isagoo muujinaya heerka caabuqa sambabada.

Utility Clinical ee FeNO

FeNO waxay ku siin kartaa xiriiriye aan fiicneyn oo loogu talagalay ogaanshaha bilowga ah ee neefta iyadoo ATS iyo NICE ay kula talinayaan qayb ka mid ah tilmaamahooda hadda iyo algorithms ogaanshaha.

Soo gaabinta: ATS, American Thoracic Society;FeNO, nitric oxide oo jajab ah oo la sii daayay;GINA, Hindisaha Caalamiga ah ee Neefta;ICS, corticosteroid neefta;NICE, Machadka Qaranka ee Caafimaadka iyo Wanaajinta Daryeelka.

Tilmaamaha ATS waxay qeexayaan heerarka sare, dhexe, iyo heerarka FeNO ee dadka waaweyn sida> 50 ppb, 25 ilaa 50 ppb, iyo <25 ppb, siday u kala horreeyaan.Halka carruurta, heerar sare, dhexdhexaad, iyo hoose FeNO lagu sifeeyay> 35 ppb, 20 ilaa 35 ppb, iyo <20 ppb (Shaxda 1).ATS waxay ku talinaysaa isticmaalka FeNO si ay u taageerto ogaanshaha neefta halkaas oo caddayn ujeedo ah looga baahan yahay, gaar ahaan ogaanshaha caabuqa eosinophilic.ATS waxay qeexaysaa in heerarka FeNO ee sarreeya (> 50 ppb ee dadka waaweyn iyo> 35 ppb ee carruurta), marka lagu tarjumo macnaha bukaan-socodka, waxay muujinayaan in caabuqa eosinophilic uu la socdo jawaab-celinta corticosteroid ee bukaanka calaamadaha, halka heerarka hooseeya (<25 ppb ee dadka waaweyn). iyo <20 ppb ee carruurta) waxay ka dhigaan mid aan macquul ahayn oo heerarka dhexe waa in si taxadar leh loo fasiro.

Tilmaamaha NICE ee hadda jira, kuwaas oo adeegsada heerarka goynta FeNO ee hooseeya marka loo eego ATS (Shaxda 1), waxay ku talinayaan isticmaalka FeNO iyada oo qayb ka ah shaqada ogaanshaha halka cudurka neefta lagu tixgaliyo dadka waaweyn ama halka ay jirto hubin la'aanta ogaanshaha ee carruurta.Heerarka FeNO ayaa mar kale lagu tarjumaa xaalad caafimaad iyo baaritaan dheeraad ah, sida baaritaanka boronkiitada kicinta ayaa laga yaabaa inay caawiso ogaanshaha iyadoo la muujinayo dareen-celinta marin-haweedka.Tilmaamaha GINA waxay qirayaan doorka FeNO ee aqoonsiga caabuqa eosinophilic ee neefta laakiin hadda ma arkin doorka FeNO ee algorithms ogaanshaha neefta.Oggolaanshaha Scottish-ku wuxuu qeexayaa goynta iyadoo loo eegayo soo-gaadhista steroid-ka ee leh qiyamka togan ee> 40 ppb ee bukaannada steroid-naive iyo> 25 ppb ee bukaannada ICS.